Creighton's academic departments administer curricula that include many courses with international content as well as majors and minors that cover studies of various areas of the world, such as:

• African Studies
• American Studies
• Asian Studies
• Classical and Near Eastern Studies
• Cultural Anthropology
• Environmental Science
• European Studies
• Global Health Equity
• International Business
• International Relations
• Justice and Peace Studies
• Latin American Studies
• Public Health
• Sustainability
   

Creighton students may also choose to study one (or more) of these modern languages:

• French
• German
• Italian
• Japanese
• Spanish

Additionally, Creighton University hosts the Encuentro Dominicano, a semester-long full-time academic, service learning, community-based learning immersive program in the Dominican Republic for undergraduate students. Using the United Nations' Sustainable Development Goals as an organizing framework, this program encourages students to consider how their major can contribute to building justice and transforming the world.

Students have multiple opportunities to study abroad through short-term and semester-long programs either sponsored by Creighton University or at outstanding partner universities and institutes around the world. Additionally, Creighton offers a variety of co-curricular opportunities abroad, including immersions, internships and international research grant opportunities through the Global Engagement Office.